Diagnosis of pseudoxanthoma elasticum [PXE] from patients presenting with bleeding per rectum

To find out rare cause of bleeding per rectum in young patients in our study of 200 patients presenting with bleeding per rectum. Department of Medicine, Nishtar Hospital, Multan. Durations From July 1998 to July 2000. Two hundred patients presenting with bleeding per rectum were studied. History, general physical examination and systemic examination were done. Then provision clinical diagnosis was made and related investigations were done to confirm the diagnosis. Out of these 200 patients, 164 patients were diagnosed as having bleeding esophageal varices due to cirrhosis of liver. 22 patients were diagnosed as having gastritis [commonly drug induced] on endoscopy, 6 patients were having bleeding hemorrhoids, 3 patients were having bleeding gastric ulcer and 5 patients were diagnosed as having PXE. When young patients presented with bleeding per rectum and if diagnosis become difficult, then PXE must be considered in these patients and investigated properly

Study of 30 Cases of FUO [Fever of Unknown Origin]

To diagnose cause of Prolonged fever in patients suffering from FUO. Patients suffering from FUO were admitted in Medical Ward in Nishtar Hospital Multan and investigations were done to find out the cause of FUO. Medical Ward, Nishtar Hospital, Multan from 1.7.1998 to 30.6.2000. Patients presenting with FUO were admitted and investigated. Out of 30 patients of FUO, causes of FUO in 27 patients were diagnosed and in 3 patients, cause of FUO could not be established but these 3 patients responded to ATT [ANTI-Tuberculous Therapy]. It has been concluded that patients suffering from FUO becomes a challenge for treating. Physician and with Intensive investigations causes of FUO can be determined in most patients and in those patients in whom causes can not be identified these can be treated with ATT and most patients respond to ATT, confirming the diagnoses of hidden Tuberculosis

Prevalence and prognosis of exercise induced non-sustained ventricular tachycardia in apparently healthy subjects

Frequent or complex patterns of ventricular ectopic activity, whether occurring during routine activity or induced by exercise, are often a marker for serious heart disease and a harbinger of sudden death. To find the prevalence, associated characteristics and prognostic significance of exercise induced non-sustained ventricular tachycardia [VT] in a representative population. This descriptive, analytical study was carried out in Nishtar Hospital, Multan during the period of one year. A total of 1000 patients were included in the study. Ten subjects, 7 men and 3 women, with exercise induced VT were identified, representing 1.1% of those tested; only 1 was young than 65 years. All episodes of VT were asymptomatic and non-sustained. In 9 of 10 subjects, VT developed at or near peak exercise. The longest run of VT was 6 beats; multiple runs of VT were present in 4 subjects. Two subjects had exercise induced ST segment depression, but subsequent exercise thallium scintigraphic results were negative in each. Compared with a group of age and sex matched control subjects, those with asymptomatic, non-sustained VT displayed no difference in exercise duration, maximal heart rate, or the prevalence of coronary risk factors or exercise induced ischemia as measured by electrocardiography and thallium scintigrahy. Over a mean follow period of 2 years, no subject has developed symptoms of heart disease or experienced syncope or sudden death. Thus, exercise induced VT in apparently healthy subjects occurs almost exclusively in the elderly, is limited to short, asymptomatic runs of 3 to 6 beats usually near peak exercise, and does not portend increased cardiovascular morbidity or mortality rates over a 2 year period of observation. Exercise induced VT in apparently healthy subjects occurs almost exclusively in the elderly, is limited to short, asymptomatic runs of 3 to 6 beats usually near peak exercise, and does not show increased cardiovascular morbidity or mortality rates over a 2 year period of observation